Kimetto's record had stood since the Kenyan set it at the same course in 2014 but Kipchoge's run will likely take some time to break as it is the biggest improvement on the marathon record since Australian Derek Clayton shaved nearly two and a half minutes off the record in 1967.
"I lack the words to describe how I feel", said Kipchoge.
Kenyan athlete Eliud Kipchoge led the country's team in registering a stunning win at the 2018 Berlin Marathon after setting a new record of 2:1:39.
"They say you miss two times but you can't miss the third time", he said in reference to his two previous failed attempts to break the world record in Berlin.
"To be precise, I am just going to try to run my personal best".
He quickly shook off his biggest opponent, Wilson Kipsang, to make it a one-man show and with weather conditions flawless and virtually no wind, it was clear after the opening few kilometres that Kipchoge's only opponent would be the clock.
On Sunday his three pacemakers were pushed to the limit to keep the tempo high as Kipchoge dipped well below world record time at the halfway mark.
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Here, he's a point of reference. "But the average after the worldwide break was only 1.31 or 1.32". Only because after the first season the players understood the difficulty of this kind of match.
"Kipchoge hit the half way mark with one pacesetter in 57:26 minutes, way inside Kimetto world record by one minute and nine seconds before hitting 1:26:45 against Kimetto's 1" 27:38 at 30km mark. "@EliudKipchoge is a monster congrats champ I will live to remember this day it will take a generation to see another run like that", former Boston Marathon champion Wesley Korir added on Twitter.
"It was really hard, but I was prepared to run my own race early so I wasn't surprised to be alone".
"The winning time is now official and another second faster: 2:01:39 for Eliud Kipchoge!" it said.
Kimeto was impressive but Kipchoge is superhuman", remarked the commentator of the 2018 Berlin Marathon as Eliud Kipchoge galloped past the 35km mark in a time of 1: "41: "03. Canadian Brent Lakatos won the men's wheelchair race for his first marathon victory.
He equally applauded Amos Kipruto and Wilson Kipsang for scooping the second and third place respectively.
Gladys Cherono won the women's race in 2 hours, 18 minutes and 11 seconds, a new women's record for the Berlin marathon.