Ernesto Valverde will be hoping to make it two out of two, when he takes his side to Wembley Stadium.
There is no doubt that Barcelona are prioritising the Champions League this season and the club and Lionel Messi have made that clear but the Argentine insists they will not be holding back in any competition.
'It was a game we needed to win and to concede straight away destroyed the plan.
'When you start a game at this level against Barcelona you can not concede these types of chances. If you watch the first half again, how many chances did he have?
Despite the defeat Pochettino was proud of his players and said his squad were "heroes" for battling back against Barcelona.
"For 45 minutes, we didn't concede one chance to Messi - but of course when we are 2-0 down and you give more space as we are attacking", Pochettino said. In the second half, he had more space and that is hard to stop.
Krishna Kapoor, wife of filmmaker Raj Kapoor, passes away
Om Shanti", Anupam Kher wrote on the microblogging site. "My deepest condolences to the family", Soha Ali Khan posted on Twitter. Bollywood celebrities are thronging to Chembur to pay their last respects to late Raj Kapoor's wife, Krishna Raj Kapoor.
"We can't talk about topics, we need to talk about reality".
'If Moura scores the third goal we talk about heroes and the manager is the best in the world'. "I feel proud for the effort of the players".
With the central third of the pitch yellow and bare thanks to the Anthony Joshua-Alexander Povetkin world heavyweight title fight which was staged at the stadium 10 days ago, it seemed the ideal metaphor for the state of Pochettino's team at present. "But I think for Barcelona it was worse because in the history of football Barcelona always try to play along the grass". What can we do?
"With all respect to other players who have won it [Ballon d'Or], we know there is a player who is different to the others and that is Leo Messi", Rakitic said post-game. While a clash with the Blaugrana is always big, Tottenham's opening matchday defeat to Inter Milan makes the game a must-win as the North Londoners can not afford to fall behind and put pressure on themselves. "We're still thinking the same, though, that all is possible".