"Hazard is out for sure", said manager Maurizio Sarri.
The England global marked just his fourth appearance of the season with his first goals since April when on loan at Crystal Palace, and his first in a Blues shirt since April 2016.
Asked about Loftus-Cheek's performance, Sarri replied: "He is a very good player, of course, but I have a little problem".
Moses is behind Eden Hazard, William and Pedro in Sarri's pecking order of wingers and has found playing opportunities hard to come by this season, with only one start from a possible 13. Damn the tactics, mentality, work rate etc etc etc that I keep hearing - bottom line, the boy scores goals, we need goals.
"This match is not a big problem, because we have to play after five days, from the last match", said Sarri.
Six shot, three critical after shooting in Jacksonville
The Jacksonville Jaguars were playing a game against the Houston Texans at the stadium at the time of the shooting. Local media reports cited authorities as saying the shooting had had no impact on game day operations.
This will be Chelsea's first meeting with Belarusian opposition.
The high profile game had many talking points with a Man United comeback to Chelsea's late late equaliser to Jose Mourinho getting involved in a touchline fiasco with the Blues support staff. All matches were in the Europa League group stages.
Loftus-Cheek, who has made only two appearances for a combined 33 minutes for Chelsea in the top-flight this season, was handed a rare start at Stamford Bridge and he responded by scoring twice inside the opening eight minutes.
BATE's win at MOL Vidi on matchday one ended a run of 12 away games without a win in major European competition, excluding qualifiers (D2, L10).
I need to come and get on the ball, connect with the midfielders and the wingers, and then I need to attack the box after that - but not to be in the box all the time. However, just 10 of these have been on target (20%), with just two finding the net (4%).